Author

Mohammed Jamshad

University of Birmingham

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 3 Biophysics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:protein structure prediction· 3 Organism:E. coli· 2 Organism:human· 2 Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Damon HuberiD· 3 shared Alexander J. GarviniD· 2 shared Joanna R. MorrisiD· 2 shared Timothy J. KnowlesiD· 2 shared Alexander J. Lanz· 1 shared Alexandra K. Walker· 1 shared Amirul H. Mahadi· 1 shared Anoop Singh ChauhaniD· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersMolecular Biology

Damon HuberORCID

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Author profile →

5 papers

Recent·Most cited

Pin1-promoted SUMOylation of RNF168 restrains its chromatin accumulation.

Anoop Singh Chauhan, Alexander J. Garvin, Mohammed Jamshad, Joanna R. Morris

This study identifies Pin1-promoted SUMOylation of RNF168 as a mechanism to restrict its chromatin accumulation at DNA damage sites, linking it to cellular radioresistance.

bioRxiv · Mar 22, 2022 · PreprintMolecular Biology

The SUMO activating enzyme subunit, SAE2, contributes SUMO protein bias for mitotic fidelity.

Alexandra K. Walker, Alexander J. Lanz, Mohammed Jamshad, Alexander J. Garvin, Peter J. Wotherspoon, Benjamin F Cooper, Timothy J. Knowles, Joanna R. Morris

This study shows that SAE2 deacetylation during mitosis biases SUMO2 over SUMO1 conjugation, affecting mitotic fidelity through SUMOylation of NuMA.

bioRxiv · Mar 18, 2022 · PreprintMolecular Biology

AscA (YecA) is a molecular chaperone involved in Sec-dependent protein translocation in Escherichia coli

Tamar Cranford Smith, Max Wynne, Cailean Carter, Chen Jiang, Mohammed Jamshad, Mathew T. Milner, Yousra Djouider, Emily Hutchinson, Peter A. Lund, Ian R. Henderson, Damon Huber

This paper identifies AscA (YecA) as a novel molecular chaperone that facilitates Sec-dependent protein translocation in E. coli by interacting with SecB and ribosomes.

bioRxiv · Jul 21, 2020 · PreprintMolecular Biology

Genetic screen suggests an alternative mechanism for azide-mediated inhibition of SecA

Rachael Chandler, Mohammed Jamshad, Jack Yule, Ashley Robinson, Farhana Alam, Karl A. Dunne, Naomi Nabi, Ian Henderson, Damon Huber

The paper uses a genetic screen to show azide inhibits SecA by causing it to backtrack in its ATPase cycle, disrupting membrane and metal cofactor binding.

bioRxiv · Aug 22, 2018 · PreprintMicrobiology

Evidence for phospholipid export from the gram-negative inner membrane: time to rethink the Mla pathway?

Gareth W. Hughes, Stephen C. L. Hall, Claire S. Laxton, Pooja Sridhar, Amirul H. Mahadi, Caitlin Hatton, Thomas J. Piggot, Mohammed Jamshad, Vaclav Spana, Cadby T. Ian, Christopher Harding, Georgia L. Isom, Jack Bryant, Rebecca J. Parr, Yasin Yakub, , Timothy J. Knowles

The paper solves the crystal structure of MlaC and shows the Mla pathway exports phospholipids from the inner membrane to the periplasm, challenging the previous belief in retrograde transport.

bioRxiv · Aug 9, 2018 · PreprintBiophysics