Author

Alexandra B Figueroa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Developmental Biology· 2 Bioengineering· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:development & morphogenesis· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Alexander David NoblettiD· 4 shared Bruna da Silveira PaulseniD· 4 shared Christian Clark KrammeiD· 4 shared Ferran BarrachinaiD· 4 shared Kathryn S. PottsiD· 4 shared Maria MarchanteiD· 4 shared Sabrina Piechota· 4 shared Alexa Giovannini· 3 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersDevelopmental Biology

Alexander David NoblettORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Ovarian support cell in vitro maturation (OSC-IVM) results in healthy murine live births with no evidence of reprotoxicology in a multigenerational study

Maria Marchante, Ferran Barrachina, Enric Mestres, Mònica Acacio, Kathryn S. Potts, Sabrina Piechota, Bruna da Silveira Paulsen, Alexander David Noblett, Alexandra B Figueroa, Nuno Costa-Borges, Christian Clark Kramme

This study shows that using human stem cell-derived ovarian support cells for in vitro maturation in mice leads to healthy live births without reprotoxic effects across generations.

Reproductive BioMedicine Online · Oct 28, 2024Peer-reviewedPharmacology & Toxicology

Reproducible differentiation of pure ovarian support cells from clinical-grade hiPSCs as a novel infertility treatment

Bruna da Silveira Paulsen, Ferran Barrachina, Alexander David Noblett, Mark Johnson, Simone Kats, Sabrina Piechota, Maria Marchante, Alexandra B Figueroa, Kathryn S. Potts, Graham N. Rockwell, Alexa Giovannini, Christian Clark Kramme

The paper describes the development of a clinical-grade hiPSC-derived ovarian support cell protocol to improve in vitro maturation of oocytes and embryo formation.

bioRxiv · Apr 29, 2024 · PreprintBioengineering

Human induced pluripotent stem cell-derived ovarian support cell co-culture improves oocyte maturation in vitro after abbreviated gonadotropin stimulation

Sabrina Piechota, Maria Marchante, Alexa Giovannini, Bruna da Silveira Paulsen, Kathryn S. Potts, Graham N. Rockwell, Caroline Aschenberger, Alexander David Noblett, Alexandra B Figueroa, Marta Sanchez, Ferran Barrachina, Klaus Wiemer, Luis Guzmán, Pedro Belchin, Merrick Pierson Smela, , Christian Clark Kramme

This study shows that co-culturing human oocytes with ovarian support cells improves in vitro maturation rates and blastocyst formation compared to standard IVM methods.

Human Reproduction · Sep 26, 2023Peer-reviewedDevelopmental Biology

Improved rescue of immature oocytes obtained from conventional gonadotropin stimulation cycles via human induced pluripotent stem cell-derived ovarian support cell co-culture

Alexa Giovannini, Sabrina Piechota, Maria Marchante, Kathryn S. Potts, Graham Rockwell, Bruna da Silveira Paulsen, Alexander David Noblett, Samantha Lauren Estevez, Alexandra B Figueroa, Caroline Aschenberger, Dawn A. Kelk, Marcy Forti, Shelby Marcinyshyn, Ferran Barrachina, Klaus Wiemer, , Christian Clark Kramme

This study shows that co-culturing immature human oocytes with hiPSC-derived ovarian support cells improves in vitro maturation rates and transcriptomic similarity to in vivo matured oocytes.

bioRxiv · Mar 27, 2023 · PreprintDevelopmental Biology