Dual Lineage Tracing Identifies Cellular Mechanisms Underlying Radiation-Associated Changes in Atherosclerotic Lesion Composition
Rebecca A. Deaton, Tajbir Raihan, Victoria M. Milosek, Fatema Allaham, Alexandra L. Krinsky, Laura S. Shankman, Alexander M. Como, Gabriel F. Alencar, Anita Salamon, Nazanin Moradinasab, Subhashis Banerjee, Gary K. Owens
This study uses dual lineage tracing to show irradiation reduces SMC investment in atherosclerotic lesions and increases EC-derived cells, leading to reduced plaque stability.
Arteriosclerosis Thrombosis and Vascular Biology · Aug 6, 2026Peer-reviewedPhysiology