Manuel Mayr

This study investigates how ZC3HC1 deficiency affects vascular smooth muscle cell behavior and neointima formation using in vitro and in vivo models.

This study shows that dietary glutamine restriction reduces atherosclerotic plaque rupture mortality by promoting fibrotic smooth muscle cell phenotypes in mice.

The paper identifies female-biased VSMC gene regulatory networks and highlights MYH9 as a key regulator of fibrous plaque phenotype in females.

The paper identifies a conserved gene signature associated with right ventricular failure in both rat and human hearts through transcriptomic analysis and validation.

This study identifies lncRNA Bigheart as a key regulator of calcineurin-NFAT signaling in myocardial hypertrophy, showing its role in driving maladaptive hypertrophy and susceptibility to heart failure.

This study performs a meta-analysis of scRNA-seq datasets to map human atherosclerosis cell diversity and identifies disease-relevant vascular cell states and markers.