Author

Alexandra M. Birrell

The University of Melbourne

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Alexander Charles LewisiD· 1 shared Andrew H. WeiiD· 1 shared Ann E. FrazieriD· 1 shared Caitlin L. RoweiD· 1 shared Carlos OpazoiD· 1 shared Celeste MawaliD· 1 shared Ching‐Seng AngiD· 1 shared David A. StroudiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Alexander Charles LewisORCID

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Author profile →

1 paper

Recent·Most cited

Inhibition of heme biosynthesis triggers cuproptosis in acute myeloid leukaemia.

Alexander Charles Lewis, Emily Gruber, Rheana L. Franich, Jessica M. Armstrong, Madison J. Kelly, Carlos Opazo, Yau Chung Low, Léa Flippe, Kevin Julio Wijanarko, Caitlin L. Rowe, Celeste Mawal, Alexandra M. Birrell, Joan So, Srimayee Vaidyanathan, Keziah Ting, , Lev M. Kats

This study identifies heme biosynthesis as a selective dependency in AML, showing that its inhibition triggers cuproptosis via copper accumulation and reveals synthetic lethal pathways for therapeutic strategies.

Cell · Nov 19, 2025Peer-reviewedCancer Biology