Author

Srimayee Vaidyanathan

The University of MelbourneORCID 0009-0007-3777-6661Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Organism:mouse· 1

Frequent Co-Authors

Kristin BrowniD· 2 shared Alexander Charles LewisiD· 1 shared Alexandra M. Birrell· 1 shared Andrew Graham CoxiD· 1 shared Andrew H. WeiiD· 1 shared Ann E. FrazieriD· 1 shared Caitlin L. RoweiD· 1 shared Carlos OpazoiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCell Biology

Kristin BrownORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintFeb 17, 2026

Cholesterol remodels the endoplasmic reticulum to control myofibroblastic CAF function

Srimayee Vaidyanathan, Nicole Laurencia Yuwono, Ellie T. Y. Mok…·Kristin Brown

This study shows that cholesterol biosynthesis is critical for myofibroblastic CAFs to remodel the extracellular matrix and promote tumor metastasis.

DOI 10.64898/2026.02.16.706237

humanexperimental assay

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Cancer BiologyCellPeer-reviewedNov 19, 2025

Inhibition of heme biosynthesis triggers cuproptosis in acute myeloid leukaemia.

Alexander Charles Lewis, Emily Gruber, Rheana L. Franich…·Lev M. Kats

This study identifies heme biosynthesis as a selective dependency in AML, showing that its inhibition triggers cuproptosis via copper accumulation and reveals synthetic lethal pathways for therapeutic strategies.

38 citationstop 1%

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