Protein nanoparticle vaccines induce potent neutralizing antibody responses against MERS-CoV
Cara W. Chao, Kaitlin R. Sprouse, Marcos C. Miranda, Nicholas J. Catanzaro, Miranda L. Hubbard, Amin Addetia, Cameron Stewart, Jack T. Brown, Annie Dosey, Adian Valdez, Rashmi Ravichandran, Grace G. Hendricks, Maggie Ahlrichs, Craig Dobbins, Alexis Hand, , Neil P. King
This study develops MERS-CoV vaccines using a protein nanoparticle platform, showing they induce strong neutralizing antibodies and protect mice against MERS-CoV challenge.
bioRxiv · Mar 13, 2024Immunology