Author

Craig Dobbins

University of Washington

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein design· 2 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:protein sequence· 1 Assay:protein structure· 1

Frequent Co-Authors

Brian CoventryiD· 2 shared A G MurrayiD· 1 shared Abigail E. BurtneriD· 1 shared Adam M. Chazin-GrayiD· 1 shared Adri Tran-Pearson· 1 shared Anitra C. Wolf· 1 shared Ayesha MisquithiD· 1 shared Buwei HuangiD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiochemistry

Brian CoventryORCID

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2 papers

Recent·Most cited

De novo design of protein minibinder agonists of TLR3

Chloe S. Adams, Hyojin Kim, Abigail E. Burtner, Dong Sun Lee, Craig Dobbins, Cameron Criswell, Brian Coventry, Adri Tran-Pearson, Ho Min Kim, Neil P. King

This study designs protein minibinders that act as agonists for TLR3, showing nanomolar binding and biological activity in cell lines.

bioRxiv · Apr 17, 2024Biochemistry

Designed Endocytosis-Triggering Proteins mediate Targeted Degradation and amplify signaling

Buwei Huang, Mohamad H. Abedi, Green Ahn, Brian Coventry, Isaac Sappington, Rong Wang, Thomas Schlichthaerle, Jason Z. Zhang, Yujia Wang, Inna Goreshnik, Ching Wen Chiu, Adam M. Chazin-Gray, Sidney Chan, Stacey Gerben, A G Murray, , David A. Baker

The paper designs EndoTags to trigger endocytosis and degradation of target proteins, enabling tissue-specific targeting and therapeutic applications.

bioRxiv · Aug 19, 2023 · PreprintSynthetic Biology