Author

Alfredo Lucas

University of California San DiegoPrimary ORCID profile (0000-0001-9439-735X · 7 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

Alfredo LucasiD7 papers · University of Pennsylvania

Biology Disciplines

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

Alexander Thomas WilliamsiD· 1 shared Birte Dowerg· 1 shared Christian M. MetalloiD· 1 shared Emeline JouliaiD· 1 shared Hanna F Willenbockel· 1 shared Mack B. ReynoldsiD· 1 shared Maureen L. RuchhoeftiD· 1 shared Pedro CabralesiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperCell Biology

Alexander Thomas WilliamsORCID

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1 paper

Recent·Most cited

In vivo itaconate tracing reveals degradation pathway and turnover kinetics

Hanna F Willenbockel, Alexander Thomas Williams, Alfredo Lucas, Mack B. Reynolds, Emeline Joulia, Maureen L. Ruchhoeft, Birte Dowerg, Pedro Cabrales, Christian M. Metallo, Thekla Cordes

This study uses mass spectrometry and in vivo 13C tracing to show itaconate is rapidly cleared from plasma, excreted in urine, and metabolized in the liver and kidneys.

Nature Metabolism · Sep 10, 2025Peer-reviewedCell Biology