Author

Ali ElSheikh

Northwestern University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Approach:benchmark study· 1 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Han Liu· 2 shared Alan B CooperiD· 1 shared Aly Azeem KhaniD· 1 shared Jason F. Perera· 1 shared Jerry Yao-Chieh HU· 1 shared Joanna K ChorazeczewskiiD· 1 shared Jutin Kline· 1 shared Lishi XieiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersImmunology

Han Liu

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Harnessing the PRDM1-PGC1A axis to enhance CAR T cell efficacy

Sidney YY Wang, Xiufen Chen, Xubin Li, Ali ElSheikh, Alan B Cooper, Joanna K Chorazeczewski, Lishi Xie, Jerry Yao-Chieh HU, Han Liu, Michael R. Green, Jutin Kline

This study identifies the PRDM1-PGC1A axis as a key regulator of CAR T cell function, showing that inhibiting PRDM1 or activating PGC1A improves CAR T cell efficacy in multiple tumor models.

bioRxiv · Oct 21, 2026 · PreprintImmunology

Virtual Cells Need Context, Not Just Scale

Payam Dibaeinia, Sudarshan Babu, Mei K. Knudson, Ali ElSheikh, Yibo Wen, Han Liu, Jason F. Perera, Aly Azeem Khan

The paper argues that scaling model capacity alone is insufficient for Virtual Cells, emphasizing the need for contextual diversity and causal representation learning over data volume.

bioRxiv · Feb 9, 2026 · PreprintGenomics