Author

Joanna K Chorazeczewski

University of ChicagoORCID 0000-0002-1212-7741Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:flow cytometry· 1

Frequent Co-Authors

Alan B CooperiD· 1 shared Alan Cooper· 1 shared Ali ElSheikh· 1 shared Brian D. BrowniD· 1 shared Daniel CharytonowicziD· 1 shared Gvantsa PantsulaiaiD· 1 shared Han Liu· 1 shared Ivan OdakiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

Alan B CooperORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintOct 21, 2026

Harnessing the PRDM1-PGC1A axis to enhance CAR T cell efficacy

Sidney YY Wang, Xiufen Chen, Xubin Li…·Jutin Kline

This study identifies the PRDM1-PGC1A axis as a key regulator of CAR T cell function, showing that inhibiting PRDM1 or activating PGC1A improves CAR T cell efficacy in multiple tumor models.

DOI 10.64898/2026.10.15.759372

humanstatistical model

𝕏 PostBluesky

ImmunologybioRxivPreprintSep 22, 2025

Potentiating CAR-T bystander killing by enhanced Fas/FasL signaling mitigates antigen escape in heterogeneous tumors

Matthew Junda Lin, Joanna K Chorazeczewski, Gvantsa Pantsulaia…·Joshua Brody

This study shows that enhancing Fas/FasL signaling improves CAR-T cell bystander killing against antigen-negative tumor cells, reducing antigen escape and improving therapeutic outcomes.

3 citations

humanmouse

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