Author

Alina Sami

University of Saskatchewan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Abhishek BoseiD· 1 shared Bhavneet BhinderiD· 1 shared Bishoy M. FaltasiD· 1 shared Duy D. NguyeniD· 1 shared Jeannine GerhardtiD· 1 shared Kent William MouwiD· 1 shared Linda ChelicoiD· 1 shared Madhura DeshpandeiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Abhishek BoseORCID

Mutual co-authors in cluster

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1 paper

Recent·Most cited

APOBEC3A-Induced DNA Damage Drives Polymerase Theta Dependency and Synthetic Lethality in Cancer

Abhishek Bose, Weisi Liu, Paul Yoo, Alina Sami, Michal T. Boniecki, Madhura Deshpande, Mohamed Hosny Abdo Osman, Duy D. Nguyen, Urko del Castillo, Paraskevi Giannakakou, Bhavneet Bhinder, William F. Hooper, Olivier Elemento, Nicolas Robine, Milaid Granadillo, , Bishoy M. Faltas

This study identifies TMEJ as the main repair pathway for APOBEC3A-induced DSBs and shows Polθ inhibition causes synthetic lethality in cancer cells with APOBEC3A activity.

bioRxiv · Oct 21, 2025 · PreprintCancer Biology