Productive mRNA Chromatin Escape is Promoted by PRMT5 Methylation of SNRPB
Joseph D. DeAngelo, Maxim I. Maron, Jacob S. Roth, Subray S. Hegde, Aliza M. Silverstein, Varun Gupta, Stephanie Stransky, Joel Basken, Joey Azofeifa, Charles C. Query, Simone Sidoli, Matthew J. Gamble, David Shechter
The paper shows PRMT5 promotes chromatin escape of mRNAs by methylating SNRPB, affecting splicing and nuclear export.
Molecular Cell · Oct 15, 2025Peer-reviewedMolecular Biology