Molecular BiologyNature Structural & Molecular BiologyPeer-reviewed
Epigenetic therapy targets the 3D epigenome in endocrine-resistant breast cancer
Joanna Achinger-Kawecka, Clare Stirzaker, Neil Portman…·Susan J. Clark
This study shows that Decitabine suppresses tumour growth in ER+ breast cancer by inducing DNA hypomethylation and altering 3D chromatin structure.
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