The SARM1 TIR domain produces glycocyclic ADPR molecules as minor products
Jeremy Garb, Gil Amitai, Allen Lu, Gal Ofir, Alexander S. Brandis, Tevie Mehlman, Philip J. Kranzusch, Rotem Sorek
This study shows that SARM1 TIR domains produce minor amounts of glycocyclic ADPR molecules in vitro and in bacterial cells, suggesting a potential role in axonal death.
PLoS ONE · Apr 18, 2024Peer-reviewedMolecular Biology