Author

Allyson Sherman‐Roe

Brown University

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Cell Biology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1

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Anthony M. ReginatoiD· 1 shared Bedia AkosmaniD· 1 shared Christopher J. RhodesiD· 1 shared Corey E. VentetuoloiD· 1 shared Eui Young SoiD· 1 shared James R. KlingeriD· 1 shared Lan ZhaoiD· 1 shared Mandy Pereira· 1 shared

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2026-2026 · peak 1/yr

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Anthony M. ReginatoORCID

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1 paper

Recent·Most cited

Cell BiologybioRxivPreprintMay 15, 2026

Impaired SOX17 Expression Causes Endothelial Dysfunction and Pulmonary Arterial Hypertension by Insufficient Suppression of RUNX1

Bedia Akosman, Moon Jung Choi, Yamini Sharma…·Olin D. Liang

This study shows that impaired SOX17 expression increases pulmonary arterial hypertension risk by failing to suppress RUNX1, leading to endothelial dysfunction, and that RUNX1 inhibition can mitigate this condition.

DOI 10.64898/2026.05.14.725187

humanbulk RNA-seq

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