Author

Yamini Sharma

Brown University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Molecular Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:imaging· 1

Frequent Co-Authors

Bedia AkosmaniD· 2 shared Corey E. VentetuoloiD· 2 shared James R. KlingeriD· 2 shared Lan ZhaoiD· 2 shared Mandy Pereira· 2 shared Martin R. WilkinsiD· 2 shared Navneet SinghiD· 2 shared Olin D. LiangiD· 2 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersPharmacology & Toxicology

Bedia AkosmanORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Identification of drug candidates for rescue of SOX17 gene targets in pulmonary arterial hypertension

Eleni Vasilaki, Bedia Akosman, Shanshan Song, Rachel Walters, Yamini Sharma, Mandy Pereira, Merve Keleş, Nadiya V Mykytyuk, Hannah Maude, Navneet Singh, George Field, Corey E. Ventetuolo, Luke Howard, Jurjan Aman, Martin R. Wilkins, , Christopher J. Rhodes

The paper identifies BX-912 as a compound that rescues SOX17 gene targets and prevents pulmonary hypertension in mice.

bioRxiv · May 21, 2026 · PreprintPharmacology & Toxicology

Impaired SOX17 Expression Causes Endothelial Dysfunction and Pulmonary Arterial Hypertension by Insufficient Suppression of RUNX1

Bedia Akosman, Moon Jung Choi, Yamini Sharma, Mandy Pereira, Young Eun Lee, Eui Young So, Allyson Sherman‐Roe, Navneet Singh, Anthony M. Reginato, Corey E. Ventetuolo, Martin Wilkins, Lan Zhao, Christopher J. Rhodes, James R. Klinger, Olin D. Liang

This study shows that impaired SOX17 expression increases pulmonary arterial hypertension risk by failing to suppress RUNX1, leading to endothelial dysfunction, and that RUNX1 inhibition can mitigate this condition.

bioRxiv · May 15, 2026 · PreprintCell Biology

Simultaneous PET and molecular MR imaging of cardiopulmonary fibrosis in a mouse model of left ventricular dysfunction

Brianna F. Moon, Iris Yuwen Zhou, Yingying Ning, Yin‐Ching Iris Chen, Mariane Le Fur, Sergey Shuvaev, Eman A. Akam, Hua Ma, Cesar Molinos Solsona, Jonah Weigand‐Whittier, Nicholas Joseph Rotile, Lida P. Hariri, Matthew Drummond, Avery T. Boice, Samantha E. Zygmont, , Krishna C. Penumatsa

This study uses PET-MRI to detect cardiopulmonary fibrosis in a mouse model of left ventricular dysfunction, showing increased signals correlate with fibrotic markers.

bioRxiv · Dec 15, 2023 · PreprintMolecular Biology