Olin D. Liang

The paper identifies BX-912 as a compound that rescues SOX17 gene targets and prevents pulmonary hypertension in mice.

This study shows that impaired SOX17 expression increases pulmonary arterial hypertension risk by failing to suppress RUNX1, leading to endothelial dysfunction, and that RUNX1 inhibition can mitigate this condition.

This paper demonstrates that combining oncolytic adenovirus encoding bispecific T cell engager (OV-BiTE) with CAR-T cells enhances T cell recruitment and tumor eradication in glioblastoma xenograft models.

This study identifies subclinical liver dysfunction clusters in PAH patients and links them to pulmonary vascular resistance and immune signaling changes.

The paper investigates the role of hepatic MYDGF in pulmonary arterial hypertension, showing its protective effects in experimental models but paradoxical associations in human data.

This study shows that myeloid-specific SHIP1 ablation enhances MDSC expansion and regulatory function in inflammatory arthritis, offering potential therapeutic applications.