Author

Christopher J. Rhodes

Hammersmith HospitalORCID 0000-0002-4852-516XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

Martin WilkinsiD· 2 shared Adam J. BrownsteiniD· 1 shared Allyson Sherman‐Roe· 1 shared Anthony M. ReginatoiD· 1 shared Bedia AkosmaniD· 1 shared Candance Guerrero· 1 shared Corey E. VentetuoloiD· 1 shared Emilia M. Swietlik· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersMolecular Biology

Martin WilkinsORCID

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2 papers

Recent·Most cited

Impaired Lung BCAA Metabolism Promotes Ferroptosis and Resultant Pulmonary Arterial Hypertension-Associated Hepatopathy

Madelyn J. Blake, Jason S. Hong, Adam J. Brownstein, Christopher J. Rhodes, Emilia M. Swietlik, Jeffrey C. Blake, Ryan A. Moon, Lynn M. Hartweck, Jenna B. Mendelson, Sasha Z. Prisco, Todd W. Markowski, LeeAnn Higgins, Kevin J. Murray, Candance Guerrero, Sandra Breuils‐Bonnet, , Kurt W. Prins

This study shows that impaired BCAA metabolism promotes ferroptosis, leading to pulmonary arterial hypertension and associated liver disease, and that targeting BCAA metabolism can alleviate these effects.

JACC Basic to Translational Science · May 30, 2026Peer-reviewedMolecular Biology

Impaired SOX17 Expression Causes Endothelial Dysfunction and Pulmonary Arterial Hypertension by Insufficient Suppression of RUNX1

Bedia Akosman, Moon Jung Choi, Yamini Sharma, Mandy Pereira, Young Eun Lee, Eui Young So, Allyson Sherman‐Roe, Navneet Singh, Anthony M. Reginato, Corey E. Ventetuolo, Martin Wilkins, Lan Zhao, Christopher J. Rhodes, James R. Klinger, Olin D. Liang

This study shows that impaired SOX17 expression increases pulmonary arterial hypertension risk by failing to suppress RUNX1, leading to endothelial dysfunction, and that RUNX1 inhibition can mitigate this condition.

bioRxiv · May 15, 2026 · PreprintCell Biology