Author

Alper Topuz

Forschungszentrum Jülich

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Approach:simulation· 1

Frequent Co-Authors

Dmitry A. FedosoviD· 2 shared Alexander Thomas BaueriD· 1 shared Berta PuigiD· 1 shared Christian GorzelannyiD· 1 shared Christian WagneriD· 1 shared Gerd BendasiD· 1 shared Katrin Nekipelov· 1 shared Kirill KorneeviD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

Dmitry A. FedosovORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Binding of extracellular vesicles to stretched von Willebrand factor promotes platelet activation

Yuanyuan Wang, Xiaobo Liu, Tomasz Downar, Alper Topuz, Alexander Thomas Bauer, Katrin Nekipelov, Santra Brenna, Gerd Bendas, Berta Puig, Stefan W. Schneider, Dmitry A. Fedosov, Christian Gorzelanny

The paper shows that extracellular vesicles bind to stretched von Willebrand factor, promoting platelet activation and aggregation, which can trap circulating tumor cells.

bioRxiv · Apr 30, 2025 · PreprintCancer Biology

Aggregation and disaggregation of red blood cells: depletion versus bridging

Nicolás Moreno, Kirill Korneev, А. Н. Семенов, Alper Topuz, Thomas John, M. P. Lettinga, Marco Ellero, Christian Wagner, Dmitry A. Fedosov

This study investigates RBC aggregation and disaggregation mechanisms using simulations, finding depletion interactions dominate aggregation while both mechanisms contribute to disaggregation.

Biophysical Journal · Mar 13, 2025Peer-reviewedBiophysics