Author

Gerd Bendas

University of BonnORCID 0000-0002-8667-7201Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

Alexander Thomas BaueriD· 1 shared Alper Topuz· 1 shared Berta PuigiD· 1 shared Christian GorzelannyiD· 1 shared Dmitry A. FedosoviD· 1 shared Felix FelleriD· 1 shared Finn Kristian HanseniD· 1 shared Irina HoniniD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

Alexander Thomas BauerORCID

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2 papers

Recent·Most cited

Binding of extracellular vesicles to stretched von Willebrand factor promotes platelet activation

Yuanyuan Wang, Xiaobo Liu, Tomasz Downar, Alper Topuz, Alexander Thomas Bauer, Katrin Nekipelov, Santra Brenna, Gerd Bendas, Berta Puig, Stefan W. Schneider, Dmitry A. Fedosov, Christian Gorzelanny

The paper shows that extracellular vesicles bind to stretched von Willebrand factor, promoting platelet activation and aggregation, which can trap circulating tumor cells.

bioRxiv · Apr 30, 2025 · PreprintCancer Biology

Target engagement studies and kinetic live-cell degradation assays enable the systematic characterization of HDAC6 PROTACs

Maria Hanl, Felix Feller, Irina Honin, Kathrin Tan, Martina Miranda, Linda Schäker-Hübner, Nico Bückreiß, Matthias Schiedel, Michael Gütschow, Gerd Bendas, Finn Kristian Hansen

This paper presents a NanoBRET assay to assess HDAC6 target engagement and establishes a system for kinetic live-cell degradation analysis of HDAC6 PROTACs.

bioRxiv · Mar 31, 2025 · PreprintPharmacology & Toxicology