A selective S-acyltransferase inhibitor suppresses tumor growth
Jia-Ying Lloyd Lee, Sebastian Dilones, Timothé Maujean, Asad Mohammad, Altaf Mohd, Noam Auslander, Donita C. Brady, George M. Burslem, Eric S. Witze
The paper identifies an inhibitor of S-acyltransferase ZDHHC20 that suppresses Kras mutant lung tumor growth and improves survival.
bioRxiv · Jul 18, 2024 · PreprintCancer Biology