Author

Timothé Maujean

University of PennsylvaniaORCID 0000-0002-8268-608XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Donita C. BradyiD· 2 shared George M. BurslemiD· 2 shared Ahlenne L. Abreu· 1 shared Altaf Mohd· 1 shared Andrew F. Jarvis· 1 shared Asad MohammadiD· 1 shared Eric S. WitzeiD· 1 shared Jia-Ying Lloyd LeeiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersCancer Biology

Donita C. BradyORCID

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2 papers

Recent·Most cited

Cancer BiologyACS Bio & Med Chem AuPeer-reviewedJan 23, 2026

MAPK Pathway Inhibition Reshapes Kinase Chemical Probe Reactivity Reflecting Cellular Activation States

Andrew F. Jarvis, Mohd Younis Bhat, Timothé Maujean…·Donita C. Brady

This study uses ABPP to show how MAPK pathway inhibitors alter kinase residue reactivity, reflecting conformational changes and resistance mechanisms in melanoma cells.

DOI 10.1021/acsbiomedchemau.5c00231

humanproteomics

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Cancer BiologybioRxivPreprintJul 18, 2024

A selective S-acyltransferase inhibitor suppresses tumor growth

Jia-Ying Lloyd Lee, Sebastian Dilones, Timothé Maujean…·Eric S. Witze

The paper identifies an inhibitor of S-acyltransferase ZDHHC20 that suppresses Kras mutant lung tumor growth and improves survival.

3 citations

humanproteomics

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