Author

Natalia Pietrosemoli

Institut PasteurORCID 0000-0002-3385-9976Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Alban LepailleuriD· 1 shared Ambre Dangien· 1 shared Anne M. FourieiD· 1 shared Barbara Joyce-Shaikh· 1 shared Carrie N. Arnold Greving· 1 shared Cédric LecouteyiD· 1 shared Christophe RochaisiD· 1 shared Claire LeloupiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMicrobiology

Alban LepailleurORCID

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2 papers

Recent·Most cited

Stress-responsive Mycobacterium tuberculosis subpopulations manipulate macrophage polarization and can be targeted to limit inflammation

Laura Pokorny, Lalit Kumar Singh, Nicolas Gangneux, Margaux Pillon, Claudia Chica, Natalia Pietrosemoli, Émeline Perthame, Jose crispin Zavala-alvarado, Olivier Hebert, Christophe Rochais, Cédric Lecoutey, Alban Lepailleur, Mena Cimino, Étienne Kornobis, Marvin Albert, , Giulia Manina

The paper identifies stress-responsive Mycobacterium tuberculosis subpopulations that influence macrophage polarization and shows targeting GroEL2 can limit inflammation.

bioRxiv · Mar 15, 2026 · PreprintMicrobiology

IL-23 tunes inflammatory functions of human mucosal-associated invariant T (MAIT) cells

Laetitia Camard, Tharshana Stephen, Hanane Yahia‐Cherbal, Vincent Guillemot, Sébastien Mella, Victoire Baillet, Hélène Lopez-Maestre, Daniele Capocefalo, Laura Cantini, Claire Leloup, Julie Marsande, Katherine Garro, Juan Sienes Bailo, Ambre Dangien, Natalia Pietrosemoli, , Lars Rogge

This study identifies IL-23's role in shaping the functional plasticity of human MAIT cells, revealing its impact on autoimmunity and cytotoxic functions through AP-1 transcription factors.

iScience · Jan 25, 2025Peer-reviewedImmunology