NeuroscienceAlzheimer s Research & TherapyPeer-reviewed
Neuronal overexpression of Nrf2 reduces dystrophic neurites in 5XFAD Alzheimer's disease model mice
Katherine R. Sadleir, Karen P Gomez, Sidhanth Chandra…·Robert J. Vassar
This study shows neuronal overexpression of Nrf2 reduces dystrophic neurites in 5XFAD mice by lowering BACE1 and other proteins in these structures.
DOI 10.1186/s13195-026-02097-2