Author

Karen P Gomez

Northwestern University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Approach:statistical model· 1

Frequent Co-Authors

Ammaarah W. Khatri· 1 shared Constance L. CepkoiD· 1 shared Fabian BumbakiD· 1 shared James B. BoweriD· 1 shared Joanna Guo· 1 shared Joshua J. ZiarekiD· 1 shared Katherine R. SadleiriD· 1 shared Makenna L. LeyiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperNeuroscience

Ammaarah W. Khatri

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2 papers

Recent·Most cited

NeuroscienceAlzheimer s Research & TherapyPeer-reviewedJun 3, 2026

Neuronal overexpression of Nrf2 reduces dystrophic neurites in 5XFAD Alzheimer's disease model mice

Katherine R. Sadleir, Karen P Gomez, Sidhanth Chandra…·Robert J. Vassar

This study shows neuronal overexpression of Nrf2 reduces dystrophic neurites in 5XFAD mice by lowering BACE1 and other proteins in these structures.

DOI 10.1186/s13195-026-02097-2

mousebulk RNA-seq

𝕏 PostBluesky

BiophysicsProtein SciencePeer-reviewedJan 23, 2026

Stabilization versus flexibility: detergent-dependent trade-offs in neurotensin receptor 1 GPCR ensembles

James B. Bower, Wijnand J. C. van der Velden, Karen P Gomez…·Joshua J. Ziarek

This study investigates how different detergents affect the stability and ligand binding of neurotensin receptor 1, revealing a trade-off between structural stabilization and conformational flexibility.

1 citation

protein structureexperimental assay

𝕏 PostBluesky