Neuronal overexpression of Nrf2 reduces dystrophic neurites in 5XFAD Alzheimer's disease model mice
Katherine R. Sadleir, Karen P Gomez, Sidhanth Chandra, Makenna L. Ley, Ammaarah W. Khatri, Joanna Guo, Yunlu Xue, Constance L. Cepko, Robert J. Vassar
This study shows neuronal overexpression of Nrf2 reduces dystrophic neurites in 5XFAD mice by lowering BACE1 and other proteins in these structures.
Alzheimer s Research & Therapy · Jun 3, 2026Peer-reviewedNeuroscience