Cytokine control of systemic hypoxia tolerance in Drosophila.
Kate Ding, Prajakta Bodkhe, Byoungchun Lee, Danielle M Polan, Amy Wycislik, Tiffany Cheung, Sophie Wu, Savraj Grewal
This study identifies a cytokine-mediated signaling pathway in Drosophila that coordinates systemic hypoxia tolerance, revealing sex-specific requirements and a regulatory role for HIF-1/sima.
bioRxiv · Jun 30, 2025 · PreprintPhysiology