Genetic studies with a uracil DNA glycosylase biosensor support a role for mitochondrial UNG1 in nuclear uracil repair
Yu-Hsiu Tony Lin, Analisa M. Lott, Xingyu Liu, Layla Abdulbaki, Yanjun Chen, Michael A. Carpenter, Reuben S. Harris
The paper develops a biosensor to measure UNG activity in living cells and shows mitochondrial UNG1 contributes to nuclear uracil repair.
Nucleic Acids Research · Aug 19, 2026Peer-reviewedCell Biology