Xingyu Liu

This study shows TRIM71 promotes hair cell regeneration by reprogramming supporting cells and activating Sall4 in cochlear organoids and explants.

This paper develops a scarless genome engineering system for SARS-CoV-2 to study protease inhibitors and drug resistance mechanisms, showing improved antiviral potency when combined with drug efflux inhibitors.

The paper develops a biosensor to measure UNG activity in living cells and shows mitochondrial UNG1 contributes to nuclear uracil repair.

The paper develops two murine TNBC models with differing immunotherapy responses for studying treatment mechanisms and therapies.

This study shows human APOBEC3B does not restrict murine papillomavirus MmuPV1 replication in cellulo or in vivo, suggesting papillomaviruses have evolved mechanisms to evade this antiviral factor.

The paper identifies nuclear N-glycosylation as a novel modification that influences cell identity and is linked to neurodevelopmental disorders.

The paper introduces an unbiased proteomic platform for ATE1-based arginylation profiling, identifying 235 unique arginylation sites in human proteomes.

This study shows that carcinogen-induced DNA adducts enhance APOBEC3B-mediated mutagenesis, leading to increased mutation rates in cancer genomes.

The paper develops a PMBT system to classify lung adenocarcinoma into four subtypes based on immune and stromal features, showing distinct molecular, cellular, and prognostic characteristics.