NeuroscienceGenome biologyPeer-reviewed
Hmgb2 improves astrocyte to neuron conversion by increasing the chromatin accessibility of genes associated with neuronal maturation in a proneuronal factor-dependent manner
Priya Maddhesiya, Tjaša Lepko, Andrea Steiner-Mezzardi…·Jovica Ninkovic
The paper shows that Hmgb2 enhances astrocyte-to-neuron conversion by regulating chromatin accessibility of neuronal maturation genes in response to growth factors.