Carbon Dioxide Controls Fungal Fitness and Skin Tropism of Candida auris
Trinh Phan-Canh, Cristina Coman, Michaela Lackner, Nina Troppmair, Christoph Müller, Diana Cerbu, Saskia Seiser, Philipp Penninger, Irina Tsymala, Narakorn Khunweeraphong, Tamires A. Bitencourt, Andrej Knarr, Sabrina Jenull, Hossein Arzani, Lisa-Maria Zenz, , Karl Kuchler
This study identifies a carbonic sensing pathway (CSP) in Candida auris that enhances drug resistance and skin colonization through mechanisms involving ROS response, cell wall remodeling, and energy metabolism.
Nature Microbiology · Dec 23, 2025Peer-reviewedMicrobiology