Harry L. T. Mobley

This study shows that the cytolethal distending toxin (CDT) produced by Escherichia coli enhances urinary tract infection progression by promoting inflammation and tissue damage in mouse models.

This study identifies key sugar transporters in Proteus mirabilis that support its fitness during urinary tract infections and shows that host metabolic conditions can influence infection severity.

The paper introduces the Vaccine Ontology (VO), a standardized framework for representing vaccines and related data, enhancing data integration and AI research.

This study identifies a carbonic sensing pathway (CSP) in Candida auris that enhances drug resistance and skin colonization through mechanisms involving ROS response, cell wall remodeling, and energy metabolism.

This paper introduces a PCR-based method to measure bacterial growth rates during infection, showing it correlates with WGS-based methods and reveals UPEC growth dynamics in a mouse UTI model.

This study examines how different capsule lineages of Serratia marcescens affect infection outcomes in animal models and macrophage resistance.

The paper identifies 18 conserved fitness genes in Enterobacterales species that contribute to bacteremia pathogenesis by testing mutants in a mouse model and finding attenuation in multiple organs.

The paper integrates Tn-Seq fitness data with functional data to identify seven common fitness mechanisms across five Enterobacterales species, validating one gene's role in bacteremia and antibiotic resistance.