Oncogenic and immunomodulatory functions of SUV420H1 in HPV-negative head and neck squamous cell carcinoma.
Arfa Moshiri, Marie K. Luff, Sohyoung Kim, Meiye Jiang, Mohd Saleem Dar, Malhar Patel, Katherine McKinnon, Elijah F. Edmondson, Laura Bassel, Andrew C. Warner, Jawad Akhtar, Hui Cheng, Jocelyn Bassler, Ken Matsui, Vassiliki Saloura
This study identifies SUV420H1 as a driver in HPV-negative HNSCC, showing its role in proliferation, invasion, and immune evasion, and suggests targeting it to improve immunotherapy response.
Cell Death and Disease · Sep 23, 2026Peer-reviewedCancer Biology