Laura Bassel

This study identifies SUV420H1 as a driver in HPV-negative HNSCC, showing its role in proliferation, invasion, and immune evasion, and suggests targeting it to improve immunotherapy response.

The paper identifies CLDN3 as a tumor-selective target in SCLC using proteogenomic analysis and validates its therapeutic potential with a monoclonal antibody.

This study shows that distributed clonal deletion checkpoints prevent autoimmune disease by restricting autoreactive B cell diversification and persistence.

This study establishes patient-derived KS xenografts that maintain KSHV infection and recapitulate KS tumor gene signatures, enabling analysis of tumor microenvironment cell communications.

This study identifies E-cadherin/YAP-dependent pyruvate carboxylase expression as a metabolic driver of breast cancer progression and metastasis, with therapeutic implications for epithelial TNBC.

This study shows that HDAC inhibition with entinostat enhances immunotherapy response in SCLC by reprogramming tumor immunology and neuroendocrine status.