Surface-guided computing to quantify dynamic interactions between cell morphology and molecular signals in 3D
Felix Zhou, Virangika K. Wimalasena, Qiongjing Zou, Andrew D. Weems, Gabriel Muhire Gihana, Edward Jenkins, Bingying Chen, Bo-Jui Chang, Meghan Driscoll, Andrew J. Ewald, Gaudenz M. Danuser
The paper introduces u-Unwrap3D to map 3D cell surfaces and analyze interactions between geometry and molecular signals, revealing new dynamics in immune and tumor cell behaviors.
bioRxiv · Apr 12, 2023 · PreprintBioinformatics