Author

Andrew J. Ewald

Johns Hopkins UniversityORCID 0000-0002-1964-0740Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Andrew J. Ewald1 paper

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Organism:chicken / avian· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:imaging· 1

Frequent Co-Authors

Atul M. DeshpandeiD· 2 shared Alexandros AfthinosiD· 1 shared Alexei HernandeziD· 1 shared Alice AmitranoiD· 1 shared André ForjaziD· 1 shared Andrew D. RaddatziD· 1 shared Aneequa SundusiD· 1 shared Anneliese CeiseliD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersSystems Biology

Atul M. DeshpandeORCID

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3 papers

Recent·Most cited

Mechanochemical cues control the coupling of metabolic and migratory patterns in cancer

Alice Amitrano, Debanik Choudhury, Brent Ifemembi, Alexandros Afthinos, Konstantin V. Stoletov, Qinling Yuan, Sanjiban Nath, Bishwa Ranjan Si, Bhawana Agarwal, Gianna Graziano, Jack Gao, Anneliese Ceisel, Matthew Hauf, Sean X. Sun, Andrew J. Ewald, , Κωνσταντίνος Κωνσταντόπουλος

The paper shows that cancer cells switch between glycolysis and oxidative phosphorylation based on microenvironment stiffness, affecting their migration patterns.

bioRxiv · Aug 24, 2026 · PreprintCell Biology

Digitize your Biology! Modeling multicellular systems through interpretable cell behavior

Jeanette Johnson, Daniel R. Bergman, Heber Lima da Rocha, David L. Zhou, Eric M. Cramer, Ian C. McLean, Yoseph W. Dance, M. I. Booth, Zachary Nicholas, Tamara Y. Lopez-Vidal, Atul M. Deshpande, Randy W. Heiland, Elmar Bucher, Fatemeh Shojaeian, Matthew Dunworth, , Paul Macklin

The paper introduces a framework for mathematical modeling of multicellular systems using interpretable cell behavior rules derived from biological knowledge and multi-omics data.

Cell · Jul 26, 2025Peer-reviewedSystems Biology

Mapping the breast tumor microenvironment: proximity analysis reveals spatial relationships between macrophage subtypes and metastasis-initiating cancer cells

Eloïse M. Grasset, Atul M. Deshpande, Jae Woo Lee, Yeonju Cho, Sarah M. Shin, Erin M. Coyne, Alexei Hernandez, Xuan Yuan, Zhehao Zhang, Ashley Cimino‐Mathews, Andrew J. Ewald, Won Jin Ho

The paper uses spatial analysis to show metastasis-initiating cancer cells in breast tumors are closely associated with specific macrophage subtypes, suggesting these interactions promote metastasis.

Oncogene · Aug 20, 2024Peer-reviewedCancer Biology