CHD1 is a synthetic lethal vulnerability in MYC-driven breast cancer
Brandon Cho, Giacomo Furlan, Peter Lin, Mélissa Shen, Kirti Mittal, Andrew Mazzanti, Linda Z. Penn, Miguel Ramalho‐Santos
The paper identifies CHD1 as a synthetic lethal target in MYC-driven breast cancer, showing that its loss suppresses tumor growth and induces cell death in MYC-overexpressing models.
Oncogene · Mar 7, 2026Peer-reviewedCancer Biology