Author

Kirti Mittal

Mount Sinai Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Developmental Biology· 1 Genetics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Assay:bulk RNA-seq· 3 Approach:statistical model· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Miguel Ramalho‐SantosiD· 3 shared Lamisa Ataei· 2 shared A Heidari· 1 shared A Mikhailov· 1 shared Abdul NooriD· 1 shared Andrew Mazzanti· 1 shared Asif MiriD· 1 shared Brandon ChoiD· 1 shared

Activity by Year

2017-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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3 shared papersCancer Biology

Miguel Ramalho‐SantosORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

CHD1 is a synthetic lethal vulnerability in MYC-driven breast cancer

Brandon Cho, Giacomo Furlan, Peter Lin, Mélissa Shen, Kirti Mittal, Andrew Mazzanti, Linda Z. Penn, Miguel Ramalho‐Santos

The paper identifies CHD1 as a synthetic lethal target in MYC-driven breast cancer, showing that its loss suppresses tumor growth and induces cell death in MYC-overexpressing models.

Oncogene · Mar 7, 2026Peer-reviewedCancer Biology

Alpha satellite RNA marks the perinucleolar compartment and represses ribosomal RNA expression in naïve human embryonic stem cells

Kirti Mittal, Lamisa Ataei, Miguel Ramalho‐Santos

The paper identifies alpha satellite RNA's role in marking the perinucleolar compartment and repressing rRNA expression in naive hESCs.

bioRxiv · Jul 11, 2025 · PreprintGenomics

LINE1 promotes nuclear compartmentalization to repress the 8-cell state in embryonic stem cells

Juan Zhang, Lamisa Ataei, Liang Li Wu, Kirti Mittal, Linh Huynh, Shahil Sarajideen, Md. Abdul Mazid, David P. Cook, Daniel Trcka, Kevin Tse, Jeffrey L. Wrana, Michael M. Hoffman, Miguel Angel Esteban, Miguel Ramalho‐Santos

This paper shows that LINE1 RNA is essential for maintaining hESCs by preventing the 8C state through nuclear compartmentalization and PRC2-mediated repression.

bioRxiv · Sep 22, 2024 · PreprintDevelopmental Biology

Mapping Autosomal Recessive Intellectual Disability: Combined Microarray and Exome Sequencing Identifies 26 Novel Candidate Genes in 192 Consanguineous Families

Ricardo Harripaul, Nasim Vasli, A Mikhailov, Muhammad Rafiq, Kirti Mittal, Christian Windpassinger, Taimoor I. Sheikh, Abdul Noor, H Mahmood, Samantha I Downey, Maneesha Johnson, Kayla Vleuten, L Bell, Muhammad Ilyas, Falak Sher Khan, , John B. Vincent

Molecular Psychiatry · Apr 11, 2017Peer-reviewedGenetics