MOPRs in mouse islets of Langerhans modulate cell signaling and secretion
Michael Keith, Christine Stander, Diego De Gregorio, Andy Huang, Shannon E. Townsend, Sepideh Sheybani-Deloui, Jeffrey Marc Zigman, Jing W. Hughes, Daniel C. Castro
This study investigates how mu opioid receptors (MOPRs) in mouse islets affect cell signaling and hormone secretion, finding they modulate calcium dynamics and glucagon release.
bioRxiv · Dec 17, 2025 · PreprintPharmacology & Toxicology