Author

Diego De Gregorio

Washington University in St. LouisORCID 0000-0001-6775-5238Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Animal Behavior & Cognition· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Daniel C. CastroiD· 2 shared Andy Huang· 1 shared Christine Stander· 1 shared Jeffrey Marc ZigmaniD· 1 shared Jing W. HughesiD· 1 shared Michael KeithiD· 1 shared Sepideh Sheybani-DelouiiD· 1 shared Shannon E. TownsendiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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2 shared papersAnimal Behavior & Cognition

Daniel C. CastroORCID

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2 papers

Recent·Most cited

Animal Behavior & CognitionPhysiology & BehaviorPeer-reviewedJul 17, 2026

Pancreatic mu opioid receptors regulate metabolism and ingestive behaviors

Diego De Gregorio, Daniel C. Castro

This study investigates how mu opioid receptor (MOPR) in the pancreas affects metabolism and eating behaviors, finding sex-specific effects on body mass, glucose tolerance, and meal patterns.

DOI 10.1016/j.physbeh.2026.115449

mouseexperimental assay

𝕏 PostBluesky

Pharmacology & ToxicologybioRxivPreprintDec 17, 2025

MOPRs in mouse islets of Langerhans modulate cell signaling and secretion

Michael Keith, Christine Stander, Diego De Gregorio…·Daniel C. Castro

This study investigates how mu opioid receptors (MOPRs) in mouse islets affect cell signaling and hormone secretion, finding they modulate calcium dynamics and glucagon release.

DOI 10.64898/2025.12.15.694418

mousebulk RNA-seq

𝕏 PostBluesky