Daniel C. Castro

This study investigates how mu opioid receptor (MOPR) in the pancreas affects metabolism and eating behaviors, finding sex-specific effects on body mass, glucose tolerance, and meal patterns.

This study investigates the role of DRN enkephalin peptides in behavior by knocking them out in mice, finding altered responses to pain, avoidance, and social stimuli.

This study investigates how mu opioid receptors (MOPRs) in mouse islets affect cell signaling and hormone secretion, finding they modulate calcium dynamics and glucagon release.

This study investigates the role of mu-opioid receptors in pancreatic islet alpha cells, showing they regulate glucagon secretion and are linked to metabolic disease.

The paper identifies how specific neurons in the medial accumbens shell encode reward preference and show distinct roles in driving reward behavior.

This study identifies an endogenous opioid circuit in mice that regulates appetitive behavior through a dorsal raphe to nucleus accumbens projection.