Jeffrey Marc Zigman

This study investigates how mu opioid receptors (MOPRs) in mouse islets affect cell signaling and hormone secretion, finding they modulate calcium dynamics and glucagon release.

This study shows that GHSRs in the olfactory bulb link hunger to olfactory sensitivity, affecting food-seeking and metabolism in mice.

This study identifies a novel gut sensory ghrelin signaling pathway that regulates metabolic homeostasis through increased energy expenditure and adipose sympathetic outflow.

This study shows that ghrelin signaling in AgRP neurons integrates energy need with sensory cues to regulate AgRP activity and dopamine release in response to food.