DELE1 oligomerization promotes integrated stress response activation
Jie Yang, Kelsey R Baron, Daniel E. Pride, Anette Schneemann, Xiaoyan Guo, Wenqian Chen, Albert S. Song, Giovanni Aviles, Martin Kampmann, R. Luke Wiseman, Gabriel C. Lander
This study reports the cryo-EM structure of DELE1's C-terminal fragment, showing its oligomerization and role in activating the integrated stress response.
Nature Structural & Molecular Biology · Aug 7, 2023Peer-reviewedMolecular Biology