Author

Wenqian Chen

Scripps Research InstituteORCID 0000-0001-8867-3012Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Wenqian Chen1 paper · UCL School of Pharmacy

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2

Frequent Co-Authors

Gabriel C. LanderiD· 2 shared Jie YangiD· 2 shared Albert S. SongiD· 1 shared Anette Schneemann· 1 shared Daniel E. Pride· 1 shared Giovanni AvilesiD· 1 shared Kelsey R BaroniD· 1 shared Martin KampmanniD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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2 shared papersMolecular Biology

Gabriel C. LanderORCID

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2 papers

Recent·Most cited

Molecular BiologyNature CommunicationsPeer-reviewedJan 27, 2026

Cryo-EM structures of human ClpXP reveal mechanisms of assembly and proteolytic activation

Wenqian Chen, Gabriel C. Lander, Jie Yang

This study presents cryo-EM structures of human ClpXP, revealing mechanisms of assembly and proteolytic activation through conformational changes and interactions.

18 citationstop 1%

humanexperimental assay

𝕏 PostBluesky

Molecular BiologyNature Structural & Molecular BiologyPeer-reviewedAug 7, 2023

DELE1 oligomerization promotes integrated stress response activation

Jie Yang, Kelsey R Baron, Daniel E. Pride…·Gabriel C. Lander

This study reports the cryo-EM structure of DELE1's C-terminal fragment, showing its oligomerization and role in activating the integrated stress response.

47 citationstop 2%

humanexperimental assay

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