Inflammation-induced epigenetic memory restores oligodendrocyte progenitor cell regenerative capacity in the aged central nervous system
Sonia Cabeza‐Fernández, Sergio Niñerola, Angela Armengol-Gomis, Juan Paraíso‐Luna, Ángeles Casillas-Bajo, Jose Antonio Gomez-Sanchez, Hugo Cabedo, Ángel Barco, Alerie Guzman de la Fuente
This study shows that inflammation-induced epigenetic memory in OPCs improves remyelination in aged mice by enhancing differentiation and reducing axonal damage.
bioRxiv · May 13, 2026 · PreprintNeuroscience