Juan Paraíso‐Luna

Aging alters the distribution, stability, and transcriptional signature of engram cells

The paper examines how aging affects engram cell distribution, stability, and gene expression in mice, finding altered engram allocation and distinct transcriptional patterns in aged brains.

KAT3 Shuttling Between Neuronal Identity and Activity-Dependent Plasticity Programs Drives Large-Scale Chromatin Remodeling

The paper shows that KAT3 cofactors move between neuronal identity and activity-dependent plasticity programs, causing chromatin remodeling in hippocampal neurons.

Inflammation-induced epigenetic memory restores oligodendrocyte progenitor cell regenerative capacity in the aged central nervous system

This study shows that inflammation-induced epigenetic memory in OPCs improves remyelination in aged mice by enhancing differentiation and reducing axonal damage.