Hyperinsulinemia promotes aberrant histone acetylation in triple negative breast cancer
Parijat Senapati, Hiroyuki Kato, Michael Lee, Amy Leung, Christine Thai, Angelica Sanchez, Emily J. Gallagher, Derek LeRoith, Victoria L. Seewaldt, David Kong Ann, Dustin E. Schones
This study shows hyperinsulinemia increases histone acetylation and promotes tumor growth in TNBC via the PI3K/AKT/mTOR pathway.
Epigenetics & Chromatin · Jul 17, 2019Peer-reviewedMolecular Biology