Sex-biased Transcriptome in in vitro Produced Bovine Early Embryos
Meihong Shi, Guangsheng Li, Hannah Marie Araujo, Angie S. Lee, Jingzhi Zhang, Yoke Lee Lee, Nicole C. Riddle, Peggy R. Biga, Anne M. Bronikowski, Richard P. Meisel, James R. Walters, Tony Gamble, Gerald S. Wilkinson, Erica Larschan, Ritambhara Singh, , Jingyue Ellie Duan
This study identifies sex-biased gene expression, alternative splicing, and isoform dynamics in bovine embryos, linking male-biased metabolism to faster development and female-biased X-linked gene expression to sex-specific regulation.
Cell & Bioscience · Aug 27, 2025Peer-reviewedDevelopmental Biology