Flexible oocyte manipulation with delayed maturation and improved SCNT efficiency using induced pluripotent stem cells
Luis Henrique de Aguiar, Yoke Lee Lee, Abdallah W. Abdelhady, Prasanthi P. Koganti, Vimal Selvaraj, Soon Hon Cheong
This study improves SCNT efficiency in cattle by delaying oocyte maturation and using biPSCs as donor nuclei, resulting in higher fusion and blastocyst rates.
bioRxiv · Oct 14, 2025 · PreprintDevelopmental Biology